by Graham Pierrepoint
Alzheimer’s Disease remains a debilitating and progressive neurological illness that affects millions of people and their families all around the world – it is a condition which remains one of the most eagerly-researched, particularly as young and elderly people alike continue to struggle with their daily lives. It can be devastating for their families, too – which is why it is all the more essential that we continue to learn more about the condition and how we may be able to stave off its effects in the years to come. In promising news, there appears to have been a breakthrough at the Washington University School of Medicine – where it is being reported that mice are showing signs of full recovery from certain treatments.
The trick is – according to reports – the use of antibodies. Scientists at the university have been able to develop a specific antibody that can effectively remove protein plaques on the brain that effectively damage cognitive ability, resulting in what has been referred to as Alzheimer’s Disease on a wider scale. The antibody that has been develop seems to be able to remove such plaques altogether – while targeting a certain protein that is known to be a large player in the development of the disease. Over a period of six weeks, it’s reported that mice were provided with weekly injections in an effort to ascertain what happened to proteins and plaques – meaning that the damage done by protein build-up was effectively reverse.
This is huge news – while testing is only available at a small scale via mice at this time, a human study could prove essential to understanding and treating what has become the most common form of dementia worldwide. “By removing plaques, if we start early enough, we may be able to stop the changes to the brain that result in forgetfulness, confusion and cognitive decline,” states Dr David Holzman, leading author in the study which can be found in the Journal of Clinical Investigation.
Watch: ▶ Alzheimer’s reversed in mice, new report says
Alzheimer’s Disease is a devastating condition for both its sufferers and for those who may care for them – and the news that a potential cure for protein and plaque build-up on the brain stands to be very welcome indeed. With mice trials appearing to be a success, it may only be a matter of time before research progresses to human trials – let’s see!