While many adolescents consider going for weight loss surgeries, researchers have found one of the surgery's common side effects noticed on them. They found that common weight loss surgery for adolescents with obesity called sleeve gastrectomy has harmful effects on bones. Popular weight-loss surgery may lead to weaker bone health in teenagers, suggests study for adolescents with obesity called sleeve gastrectomy has harmful effects on bones. "Childhood obesity is a major public health issue that has increased over the last 10 years," said lead investigator Miriam A. Bredella, M.D., professor of radiology at Harvard Medical School in Boston, Massachusetts, and vice-chair of the Department of Radiology at Massachusetts General Hospital in Boston. "Sleeve gastrectomy is the most common bariatric surgery procedure performed in children and adults." In a sleeve gastrectomy, approximately 75% of the stomach is removed to restrict food intake and induce weight loss. It results in a typically round stomach taking on the shape of a tube or sleeve. The number of sleeve gastrectomy procedures performed on adolescents increased 100-fold from 2005 to 2014.
Artificial intelligence (AI) used in machine learning models can predict which patients are at highest risk for severe pain after surgery, and help determine who would most benefit from personalised pain management plans that use non-opioid alternatives, suggests new research. The research was presented at the ANESTHESIOLOGY 2020 annual meeting. Some patients experience more severe pain after surgery and need higher doses of opioids for longer periods of time, which increases their risk for opioid abuse disorder. By knowing which patients are at higher risk for severe post-surgical pain, physician anesthesiologists can create an anaesthesia plan using non-opioid alternatives - such as nerve blocks, epidurals and other medications - to more effectively address pain and reduce the need for opioids. "We plan to integrate the models with our electronic medical records to provide a prediction of post-surgical pain for each patient," said Mieke A. Soens, M.D., lead author of the study and an anesthesiologist at Brigham and Women's Hospital and anesthesiology instructor at Harvard Medical School, Boston.
Professor Danny Altmann from Imperial College London has said the positive studies showing a 90% effective Covid-19 vaccine is "terribly good news...even better than we expected". Pharmaceutical firm Pfizer announced that interim findings from its Covid-19 vaccine study showed the jab to be more than 90% effective in preventing the disease. Professor Altmann spoke with caution over the vaccine's findings, however, imploring people to "not think of this as a rapid fix", adding "we're still going to be facing a hard time for much of 2021". The Professor of Immunology did say that the new findings "means there is light at the end of the tunnel" to this global pandemic. Report by Thomasl. Like us on Facebook at http://www.facebook.com/itn and follow us on Twitter at http://twitter.com/itn
A study conducted by an international team of researchers with FAPESP's support shows that infection by chikungunya virus can produce even more severe manifestations than the typical symptoms of the disease, such as acute fever, headache, rash, and intense joint and muscle pain. The analysis was performed by 38 researchers affiliated with the Federal University of Ceara (UFC), the University of Sao Paulo (USP), and the Ministry of Health in Brazil, and with Imperial College London and Oxford University in the United Kingdom. Their main discovery was that chikungunya can infect the central nervous system and impair cognitive and motor functions. The study was conducted under the auspices of the Brazil-UK Center for Arbovirus Discovery, Diagnosis, Genomics, and Epidemiology (CADDE). It also derived from Souza's postdoctoral research, part of which he pursued at Oxford University in the UK with FAPESP's support via a Research Internship Abroad.Researchers affiliated with several different institutions collaborated on the project, which was also supported by Brazil's National Council for Scientific and Technological Development (CNPq).