On Wednesday, the US recorded 3,157 coronavirus deaths.
The stark number marks a new single-day record for deaths related to Covid-19.
More Americans died from COVID-19 on Wednesday than the number of people killed in the 9/11 terror attacks.
There have been more than 273,000 reported COVID-19 deaths in the US and over 14.5 million confirmed cases.
CDC officials warned that the coming months will be the "most difficult in the public health history" of the country.