US begins 'warp speed' vaccine push as studies ramp up

WASHINGTON (AP) — President Donald Trump vowed to use “every plane, truck and soldier” to distribute COVID-19 vaccines he hopes will be ready by year's end — even as the country's top scientists gear up for a master experiment to rapidly tell if any really work.

Trump on Friday declared the vaccine program he calls “Operation Warp Speed” will be “unlike anything our country has seen since the Manhattan Project.”

The goal is to have 300 million doses in stock by January, a huge gamble since a vaccine never has been created from scratch so fast — and one that could waste millions if shots chosen for the production line don't pan out. As the manufacturing side gets into place, the National Institutes of Health is working in parallel to speed the science.

At least four or five possible vaccines “look pretty promising” and one or two will be ready to begin large-scale testing by July with others to follow soon, NIH Director Francis Collins told The Associated Press.

"The big challenge now is to go big and everybody is about ready for that. And we want to be sure that happens in a coordinated way,” Collins said.

That year-end goal is a “very bold plan ... a stretch goal if there ever was one,” he said in an interview late Thursday.

Worldwide, about a dozen vaccine candidates are in the first stages of testing or poised to begin, small safety studies in people to look for obvious problems and whether the shots rev up the immune system. Among those getting the most attention are one created by the NIH and Moderna Inc., and a different type created by Britain’s Oxford University.

Current tests “are looking pretty good,” Collins said. “But until you put it into the real world and check it out you don’t really know. You can’t skip over...