Israel killed a top commander from the Iranian-backed Palestinian militant group Islamic Jihad in a rare targeted strike in the Gaza Strip, and militants responded by firing rockets at Israeli cities, including Tel Aviv.
In the most serious escalation in months, an Israeli missile attack also targeted the home of an Islamic Jihad official in Damascus, killing two people including one of his sons, Syrian state media said.
Israel declined any comment on that incident.
Palestinian militants fired dozens of rockets into Israel, setting off sirens as far north as Tel Aviv and prompting several municipalities to close schools.
Similar precautions were ordered in Gaza.