His brutal killing helped ignite the nation's civil rights movement.
Now the Justice Department has reopened the investigation into Emmett Till's murder saying it has discovered new information.
It's unclear what the new information is, but in a report to Congress, the U.S. Justice Department says it has revived the probe.
The black teenager was beaten, shot, and mutilated in Mississippi in 1955 after he was accused of flirting with a white woman.
The 14-year-old from Chicago was visiting relatives in rural Mississippi when he went into a store and was accused of making sexual advances at the female owner.
The woman's then-husband and another man were charged with Till's murder, but the two white men were acquitted of the crime by an all-white jury.
The pair later confessed in a magazine interview to abducting and beating Till and tossing him into the river with a 75-pound cotton gin fan tied to his neck.
The two men have since died.
In 2005, Till's body was exhumed after the FBI reopened the investigation.
But the federal case was ultimately closed in 2007 after the Justice Department concluded that the statute of limitations had expired.
There's no word yet on what the new information is that prompted investigators to re-open the case or whether prosecutors will ultimately be able to announce any new charges in connection with Till's death.