The Delhi-Meerut highway has been blocked till 3 pm amid "Bharat bandh" - a nationwide shutdown called for by farmers protesting the farm laws.
Transport services, offices and shops - particularly those selling fruits and vegetables - have been affected in some states.
Police in Delhi and Haryana, where large numbers of farmers have set up camp amid police barricades, have issued advisories to re-route traffic.
Farmer groups have emphasised this will be a "peaceful protest" and emergency services - like ambulances - will not be stopped or delayed.
Opposition parties, including the Congress, Arvind Kejriwal's AAP, DMK, TRS, have backed the Bandh.
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